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Intestinal Barrier Dysfunction: Preclinical evidence suggests that by lowering systemic oxidative stress, NAC may promote intestinal barrier integrity and support a healthy balance of intestinal microbiota, addressing the gut dysbiosis often seen in chronic illness

10.1146/annurev.immunol.18.1.621 48 KavazisA

"It's preliminary, but you can see that countries that have more ergothioneine in their diets, countries like France and Italy, also have lower incidences of neurodegenerative diseases, while people in countries like the United States, which has low amounts of ergothioneine in the diet, have a higher probability of diseases like Parkinson's Disease and Alzheimer's," said Beelman

The healthy heart is metabolically flexible and utilises a wide range of substrates for energy production, depending on factors such as oxygen availability, substrate concentration, hormone levels and workload

The relationship between concentration and results follows a curve that plateaus rather than climbing indefinitely